Sarcopenia is a process of progressive aging‐associated loss of skeletal muscle mass (SMM) recognized as a serious global health issue contributing to frailty and increased all‐cause mortality. Exercise and nutritional interventions (particularly intake of dairy products and milk) demonstrate good efficacy, safety, and broad applicability. Here, we propose that at least some of the well‐documented favorable effects of milk and milk‐derived protein supplements on SMM might be mediated by D‐galactose, a monosaccharide present in large quantities in milk in the form (...) of disaccharide lactose (milk sugar). We suggest that ingestion of dairy products results in exposure to D‐galactose in concentrations metabolized primarily via the Leloir pathway with the potential to (i) promote anabolic signaling via maintenance of growth factor (e.g., insulin‐like growth factor 1 [IGF‐1]) receptor mature glycosylation patterns; and (ii) provide extracellular (liver glycogen) and intracellular substrates for short (muscle glycolysis) and long‐term (muscle glycogen, intramyocellular lipids) energy availability. Additionally, D‐galactose might optimize the metabolic function of skeletal muscles by increasing mitochondrial content and stimulating glucose and fatty acid utilization. The proposed potential of D‐galactose to promote the accretion of SMM is discussed in the context of its therapeutic potential in sarcopenia. (shrink)

Croatia is a transitional society in that it is a country emerging from a socialist command economy toward a market-based economy with ensuing structural changes of a social and political nature—some extending into the healthcare system. A legacy from our past is that, until now, Croatian healthcare institutions have had no real experience with clinical ethics support services. When clinical cases arise presenting complex ethical dilemmas in treatment options, the challenges presented to the medical team are substantial. The case described (...) below recently occurred on a ward in a university hospital in Croatia. An unexpected request from the patient’s parents created a number of issues that needed to be addressed by the medical team, which was made more difficult by the lack of clinical ethics support services. Such cases press the question currently being debated as to what type of ethics support services would be suitable for Croatia and why. (shrink)

Depression is a major public health issue and the literature has consistently showed that the rates of depression increase dramatically during youth transition to adulthood, and gender differences merge in this period. Positive youth development framework is focused on strengths that make young people more resistant to negative outcomes, like depression, and more capable to choose a positive life direction. The aim of the study was to examine the relationship between the 5Cs of PYD and depression in Croatia and Spain, (...) as well as to analyze gender differences. This research was conducted within the PYD Cross-National Project. High school and university students from Eastern Croatia and Southern Spain participated in the study. There were 584 students from Croatia and 768 students from Spain, who filled in self-reports of PYD and depression. Results showed that male participants presented more Competence and Confidence, while female participants reported more Connection, Caring, Character, overall PYD, but also more depressive symptoms. Furthermore, Confidence and Connection were negative correlates of depressive symptoms, with neither Spain nor Croatia showing remarkable gender differences. These results may have some implications concerning the promotion of the 5Cs of PYD as a recommendable approach to promote youth mental health in Croatia and Spain from a gender perspective. Youth mental health services and initiatives that engage the partnership of youth contexts, such as the family, schools and neighborhoods, should not only address risk factors for mental health problems, but also protecting factors as the 5Cs, thus providing a more inclusive and sustainable support for youth well-being. (shrink)

The somatic mutation theory (SMT) of cancer has been and remains the prevalent theory attempting to explain how neoplasms arise and progress. This theory proposes that cancer is a clonal, cell‐based disease, and implicitly assumes that quiescence is the default state of cells in multicellular organisms. The SMT has not been rigorously tested, and several lines of evidence raise questions that are not addressed by this theory. Herein, we propose experimental strategies that may validate the SMT. We also call attention (...) to an alternative theory of carcinogenesis, the tissue organization field theory (TOFT), which posits that cancer is a tissue‐based disease and that proliferation is the default state of all cells. Based on epistemological and experimental evidence, we argue that the TOFT compellingly explains carcinogenesis, while placing it within an evolutionarily relevant context.magnified imagemagnified imageAna Soto and Carlos Sonnenschein are at Tufts University School of Medicine, Boston, MA, USA. (shrink)

Este artigo analisa os conceitos de sexualidade e gênero na contemporaneidade. Procura-se identificar as produções bibliográficas recentes em vários campos de conhecimento e seus limites e avanços epistemológicos para entender outras relações sociais e os novos contextos diaspóricos na produção de sexualidades, raça, gênero, afetividade e corpo na pós-colonialidade.

In this study we examined whether parents’ perceptions of students’ anxiety as well as perceived support from both teachers and classmates were predictive of changes in students’ academic motivation during the first wave of COVID-19. To this end, we used a retrospective pretest-posttest design together with a latent change score model to analyze our data. From April to May of 2020, 394 Portuguese parents of students in grades 1–9 participated in this study. Our results showed that students’ anxiety and teachers’ (...) social support, as perceived by parents, were highly significant predictors of academic motivation changes. Specifically, we found a negative effect of anxiety and a positive effect of teachers’ social support on students’ academic motivation. Our results did not show, however, a significant predictive role of classmates’ social support. This study provides an important contribution to further understand the intrapersonal and interpersonal factors that are associated with the decline of students’ academic motivation during the COVID-19 pandemic. The pivotal role of teachers in sustaining students’ academic motivation and other relevant educational implications for the ongoing pandemic are discussed. (shrink)

A current issue in psycholinguistic research is whether the language difficulties exhibited by children with developmental language disorder [DLD, previously labeled specific language impairment ] are due to deficits in their abilities to pick up patterns in the sensory environment, an ability known as statistical learning, and the extent to which explicit learning mechanisms can be used to compensate for those deficits. Studies designed to test the compensatory role of explicit learning mechanisms in children with DLD are, however, scarce, and (...) the few conducted so far have led to inconsistent results. This work aimed to provide new insights into the role that explicit learning mechanisms might play on implicit learning deficits in children with DLD by resorting to a new approach. This approach involved not only the collection of event-related potentials, while preschool children with DLD [relative to typical language developmental controls] were exposed to a continuous auditory stream made of the repetition of three-syllable nonsense words but, importantly, the collection of ERPs when the same children performed analogous versions of the same auditory SL task first under incidental and afterward under intentional conditions. In each of these tasks, the level of predictability of the three-syllable nonsense words embedded in the speech streams was also manipulated to mimic natural languages closely. At the end of both tasks’ exposure phase, children performed a two-alternative forced-choice task from which behavioral evidence of SL was obtained. Results from the 2-AFC tasks failed to show reliable signs of SL in both groups of children. The ERPs data showed, however, significant modulations in the N100 and N400 components, taken as neural signatures of word segmentation in the brain, even though a detailed analysis of the neural responses revealed that only children from the TLD group seem to have taken advantage of the previous knowledge to enhance SL functioning. These results suggest that children with DLD showed deficits both in implicit and explicit learning mechanisms, casting doubts on the efficiency of the interventions relying on explicit instructions to help children with DLD to overcome their language difficulties. (shrink)

Several studies prove the relevance of internal marketing in promoting job satisfaction and life satisfaction among professionals. During the COVID-19 Pandemic, educational institutions were faced with a set of challenges that forced the redefinition of strategies appropriate to the context experienced, with internal marketing being a key factor in redefining these same strategies. This study aims to evaluate whether internal marketing is a catalyst for professional satisfaction and life satisfaction among professionals in the Education industry active in Portugal during the (...) COVID-19 Pandemic. To this end, a conceptual research model was developed and 4 study hypotheses were postulated to investigate the purpose of this research based on a quantitative methodology applied to a convenience sample (n=167). The findings obtained proved to be statistically significant, showing internal marketing as a direct and positive predictor of commitment, professional satisfaction and also satisfaction with life. Besides, job satisfaction has been confirmed as a direct and positive determinant of employee performance, commitment, loyalty and satisfaction with life. Finally, commitment was too confirmed as a predictor of employee satisfaction and loyalty. Thus, this research presents itself as an added value for both science and the education industry, as it makes important contributions to the country's educational institutions and enables them to perceive various determinants of professional satisfaction, commitment, employee performance and loyalty, so as to improve strategies that support organizational sustainability and the well-being of educational agents and, in turn, of the students themselves. (shrink)

Partiendo de un enfoque desde los riesgos que el tratamiento de los datos biométricos y los sistemas de IA biométricos implican para los derechos humanos, se analiza su protección en la legislación sobre protección de datos personales y en la Propuesta de Reglamento sobre Inteligencia Artificial de la Unión Europea.

Este artigo busca analisar os efeitos estéticos que surgem do diagnóstico do filósofo esloveno Slavoj Zizek, sobre o conceito de ideologia cínica. Segundo Zizek, tal conceito não corresponde mais à definição clássica de ideologia, ou seja, de um discurso que mascara seus reais interesses. Ao contrário da forma tradicional, a ideologia cínica não oculta seus interesses particulares por trás de uma aparente universalidade ideológica, mas os assume claramente. Na sociedade capitalista contemporânea, onde emerge tal ideologia, a crítica à mimesis ou (...) a “fascinação” fetichista da realidade social tornou-se obsoleta. Este aspecto fica como fica evidente em alguns elementos da cultura capitalista como os ready-mades, a pop art, o design, os quadrinhos, o cinema comercial, a moda, a publicidade, e o entretenimento televisivo. A arte contemporânea é uma espécie de “estetizaçao”da insuficiência do desvelamento da ideologia tão almejada pelo programa estético da arte moderna. (shrink)

It would be ahistorical to ridicule vitalists. When one reads the writings of one of the leading vitalists like Driesch one is forced to agree with him that many of the basic problems of biology simply cannot be solved by a philosophy as that of Descartes, in which the organism is simply considered a machine…. The logic of the critique of the vitalists was impeccable.At the turn of the new millennium, concomitant with the development of the evo-devo and eco-devo disciplines (...) within developmental biology, critical appraisals of the reductionist stance of the molecular biology revolution became more numerous and noticeable. Several books and papers address the problems posed by this reductionist agenda and suggest... (shrink)

Spin is a fundamental and distinctive property of the electron, having far-reaching implications. Yet its purely formal treatment often blurs the physical content and meaning of the spin operator and associated observables. In this work we propose to advance in disclosing the meaning behind the formalism, by first recalling some basic facts about the one-particle spin operator. Consistently informed by and in line with the quantum formalism, we then proceed to analyse in detail the spin projection operator correlation function \=\left\langle (...) \left \left \right\rangle \) for the bipartite singlet state, and show it to be amenable to an unequivocal probabilistic reading. In particular, the calculation of \\) entails a partitioning of the probability space, which is dependent on the directions \.\) The derivation of the CHSH- or other Bell-type inequalities, on the other hand, does not consider such partitioning. This observation puts into question the applicability of Bell-type inequalities to the bipartite singlet spin state. (shrink)

Kant controversially opposed political revolutions; yet, in morality, he clearly encouraged a revolutionary attitude. Drawing especially on the relevant texts in the Metaphysics of Morals, the Religion, the Education and the Anthropology, I explore the conceptual underpinnings of Kant’s position, arguing that Kant’s contrast between moral revolution and reform is at the basis of his twofold notion of noumenal and phenomenal virtue, which in turn explains the contrast he draws between principled versus imitative behaviour in the Education. On this basis, (...) I defend the complementary role of political reform and moral revolution in his approach to cultural progress. (shrink)

Vardanyan’s Theorems [36, 37] state that $\mathsf {QPL}(\mathsf {PA})$ —the quantified provability logic of Peano Arithmetic—is $\Pi ^0_2$ complete, and in particular that this already holds when the language is restricted to a single unary predicate. Moreover, Visser and de Jonge [38] generalized this result to conclude that it is impossible to computably axiomatize the quantified provability logic of a wide class of theories. However, the proof of this fact cannot be performed in a strictly positive signature. The system $\mathsf (...) {QRC_1}$ was previously introduced by the authors [1] as a candidate first-order provability logic. Here we generalize the previously available Kripke soundness and completeness proofs, obtaining constant domain completeness. Then we show that $\mathsf {QRC_1}$ is indeed complete with respect to arithmetical semantics. This is achieved via a Solovay-type construction applied to constant domain Kripke models. As corollaries, we see that $\mathsf {QRC_1}$ is the strictly positive fragment of $\mathsf {QGL}$ and a fragment of $\mathsf {QPL}(\mathsf {PA})$. (shrink)

Prominent tuberculosis (TB) actors are invoking solidarity to motivate and justify collective action to address TB, including through intensified development and implementation (D&I) of technologies such as drugs and diagnostics. We characterize the ethical challenges associated with D&I of new TB technologies by drawing on stakeholder perspectives from 23 key informant interviews and we articulate the ethical implications of solidarity for TB technology D&I. The fundamental ethical issue facing TB technological D&I is a failure within and beyond the TB community (...) to stand in solidarity with persons with TB in addressing the complex sociopolitical contexts of technological D&I. The failure in solidarity relates to two further ethical challenges raised by respondents: skewed power dynamics that hinder D&I and uncertainties around weighing risks and benefits associated with new technologies. Respondents identified advocacy and participatory research practices as necessary to address such challenges and to motivate sustained collective action to accelerate toward TB elimination. We present the first empirical examination of bioethical accounts of solidarity in public and global health. Our study suggests that solidarity allows us better to understand and address the ethical challenges that arrest the D&I of new TB technologies. Solidarity lends credence to policies and practices that address the relational nature of illness and health through collective action. (shrink)

It is untrue that, as Hegel said in 1807 in the Phänomenologie, «the wounds of the spirit heal and leave no scar behind; what is done is not indelible, but is reassumed by the spirit» (GW 9, 360) since the ground of reality, that reality which, as indicated by Kant, seems to be submerged in evil (Ak. VI), refuses to be tamed by concepts. Disappearance without remnant, that dissolution (Verschwindung) mentioned by Hegel would suppose that there is no remnant of (...) evil, thatits effects in history-such as the Jacobin terror with its macabre liturgy of severed heads referred to in the above passage of the Phänomenologieare nothing more than moments to be sublate (aufgehoben), part of a necessary process. There is no remnant to be explained. All is revealed: Offenbarung der Tiefe. The relationship between Hegel and Schelling has in this topic, the problem of evil and its meaning in history (Geschichte), one of its key points: in Schelling one can see a hollow which constitutes a pathway to the problem of finitude and evil, studied in depth in the Freiheitsschrift of 1809, partly as a response to the critics expressed by Hegel in the Phänomenologie. While Hegel reduced evil to an abstract negation, to be overcome through a determinated negation as a sign ofthe reason in history, in Schelling evil would remain a permanent possibility that can never be dissolved (verschwinden) or overcome (aufgehoben) any way. (shrink)

This book brings together a number of contributions dealing with certain fundamental structures of practical rationality, as they are presented in the areas of the philosophy of action and normative ethics, namely: intentionality, normativity, and reflexivity. With the term “intentionality,” is meant a set of problems that are linked not only with the teleological structure of praxis-oriented rationality, but also with its temporal structure. “Normativity”, in turn, refers to a distinct set of problems, which cannot simply be reduced to those (...) entailed in the intentional nature of human action, even if this notion incorporates a reference to the good or value in its very structure. Finally, with the term “reflexivity” we point at the linkage between the normative dimension of reason with both the contingent circumstances of action and the moral receptivity of the agent, as it is experienced in moral judgment. (shrink)

As its title is meant to suggest, this paper is a reply to Sir Tim Lankester’s article “International Aid: Experience, Prospects and the Moral Case”, published in the World Economics last year 1 . Therefore, I would like to begin by expressing my gratitude for the author’s responsiveness to my interest and queries in the area of development economics. The main point of Sir Lankester’s article was, I believe, to strengthen the case for international aid by showing first, that it (...) was not just a theoretical matter 2 and second, that its efficiency was not a self-evident fait accompli, but a still-to-achieve objective, entirely contingent upon human and institutional factors such as the will, interests, and past experience of donors, as well as the system of governance and existing policies from the recipient countries. Moreover, the human factor is actually two-fold, in the sense that one can focus either on the external part engaged in the aid mission – the donor –, or on the internal one – the recipient. Sir Tim Lankester looks into what motivates the former, whereas I intend to unpack the life-experience of the latter, for I strongly believe that what ultimately decides the success or failure of development projects has more to do with understanding their life situation, than with the actual quantum of aid. Although the two cases grounded on the above-mentioned claims may seem completely separated in Tim Lankester’s article for he allocates distinct sections to them, I have reasons to believe that they are not only inter-connected, but also deeply inter-dependent, which is crucial for the kind of existentialist scenario that I intend to outline here. In order to prove this, I am going to combine two sets of argumentative tools: one will be logical, the other – empirical. The former will help us address the issues at stake in Tim Lankester’s moral case, and find ways of strengthening it; the latter will help reminding the real goal of this attempt – which is to improve the prospects of aid missions in real-life scenarios, rather than in theory. The first, rather theoretical section will consist of an extended analysis of the moral case that Sir Lankester started to build. The focus will be not only on the supposedly fruitful aspects of social justice theories, but also on their potential risks; both heroes and villains will emerge from the analysis, and new leads will be discovered. The main criterion for testing whatever findings will remain the pragmatic one: questioning their implications on the life-experiences of the poor. The other approach that I have mentioned will consist of providing a description of life in a particular community, which I have known and learnt from. In this case, the ‘empirical’ obviously means more than just the use of examples – which can be invented, or refined: it actually involves relying on a set of personal experiences and convictions, thereby testifying in – rather than just advocating – the case for aid and development projects, under discussion here. Again, the purpose will be not so much to prove that my claim has the sort of objective validity that a theoretician would normally seek to achieve, as to enforce it by whatever relevant testimonies – be them contextual, perhaps even biased; in this case, the ‘biased’ aspect consists of using an example derived from lifeexperiences in a particular developing country: my own. And it is exactly what I regard as the strength of it; indeed, I would not be writing this, had I not learnt that lesson. (shrink)

María Zambrano efetua uma abordagem do sonho enquanto fenómeno que acontece não apenas no sono, mas também na vigília. Um sonho decifrado, em termos da compreensão do fenómeno, é um sonho criador, um sonhar bem, um estado que toca a eternidade por transcender o tempo. Num momento da sua vida, Zambrano observava silenciosamente as ruínas do Fórum Romano e decifrou o sonho, compreendendo subitamente como as ruínas metaforizavam o humano. O ser humano é aquele que procura edificar os seus sonhos (...) e transcender o acabamento, fundindo-se com a natureza (o que é simbolizado pela hera que invade as ruínas). (shrink)

The intensification of farm animal welfare debate has led to an increasing number of certification schemes covering this issue; however, there are concerns about the contribution of these schemes in improving welfare. The aims of this study were to identify certification schemes for broiler chicken welfare at farm level in Brazil, to investigate the extent of nutritional, environmental, health and behavioral indicators within the schemes and to analyze the content of scheme and the capacity to promote continuous improvement on certified (...) farms. GLOBALG.A.P.® and Certified Humane® were the only schemes observed, corresponding to 2.1 % of broiler chicken farms in Brazil. Environmental and health indicators were in greater number, and the requirements classified as behavioral indicator were commonly related to the resolution of low levels of animal welfare. Both schemes were in accordance with the European Food Safety Authority recommendations for farmer training, birds and buildings inspection, temperature control, air and litter quality, stocking density and lighting. The selection of breeds and the use of animal-based indicators needs to be improved, as well the inclusion animal welfare objectives and management review as part of continuous improvement. Welfare certification is a potential market to be developed in Brazil. Overall, assessed schemes may potentially enhance animal welfare at farm level by including new concepts and practices. It is desirable to increase the number of certified farms in Brazil and that certification schemes be critically analyzed on a regular basis regarding their content to meet new demands and to include updates from scientific research. (shrink)

Publicada en 1979, Violence se desarrolla en la ciudad nigeriana de Benín, durante el boom petrolífero de la década de 1970. La narrativa se centra en dos matrimonios que representan ambos extremos del espectro social, cuyos caminos se cruzan mientras sortean diversos obstáculos. La novela de Iyayi constituye una crítica marxista de la violencia ejercida por la pobreza y la desigualdad extrema. Violence muestra cómo ciertos cuerpos humanos se cosifican y explotan de manera sistemática, a la vez que aquellos que (...) no generan ganancias son descartados sin el menor rastro de humanidad. Desde la perspectiva de la ecocrítica urbana, este artículo examina instancias de cosificación corporal en la novela y, específicamente, de comoditización de energía y materia humanas entendidas como recursos naturales. El estudio propone que Iyayi no solo critica esta comoditización al presentarla como una consecuencia del proyecto capitalista, sino que también la cuestiona mediante actos de cuidado resistente que devuelven a los cuerpos cosificados su calidad de sujeto. Estos actos de cuidado constituyen una forma de refutar la separación artificial de Naturaleza y Sociedad, contenida en el dualismo de cuerpo y mente, que históricamente ha justificado la explotación y expropiación capitalista (neo)colonial. El presente artículo contribuye entonces tanto al campo de los estudios poscoloniales como a los de ecocrítica urbana y literaturas africanas, centrándose en una obra relativamente poco analizada y en problemáticas sumamente relevantes para la Nigeria contemporánea. (shrink)

In this paper I introduce the theory of gift giving as a possible means to reconcile the contradictions inherent in accountability measures of ‘faculty productivity’ in the American university. In this paper I sketch the theory of gift economies to show how, given the historical ideals that characterize the faculty‐student relationship, a theory of gift giving could help us better judge the labor of the faculty. I suggest that it is the relational character of teaching that frustrates accountability measures and (...) that perhaps if viewed as a gift economy—and in particular an economy with ‘reproductive’ ends—we could better grasp the effectiveness of these relationships. (shrink)

Derrida dice en más de una oportunidad que la cuestión de los demás vivientes, de lo otro que lo humano, ha inquietado siempre su escritura, aún cuando no fuera tema explícito de sus formulaciones. Este trabajo busca abordar esta aseveración como una ocasión para interrogar si tal inquietud se inscribió de manera semejante en todos los casos, o si acaso a los distintos tópicos, interlocutores y, en suma, texturas que atraviesa la escritura derridiana, no siguen impactos filosóficos relevantes para el (...) enfoque de tal problema. Para ello se reelerá _La voz y el fenómeno_ a la luz de las principales tesis del plantismo tal como lo desarrollan M. Marder y J. T. Nealon, a sabiendas no obstante que las plantas no suelen constituir los vivientes no humanos a los que se refiere Derrida. En este sentido, y sin pretender mostrar un supuesto solapamiento o develar lo que en verdad Derrida habría _querido-decir_, la presente investigación busca examinar una serie de herramientas que nos parecen particularmente interesantes para abordar la subjetividad desde una perspectiva postmetafísica. (shrink)

Este artículo tiene como propósito principal investigar la famosa sentencia derridiana “il n’y a pas de hors-texte”, que como sabemos entró a significar una especie de slogan de época. En función de este propósito, realizamos un examen del contexto de aparición más inmediato de la mentada frase, estudiamos sus condiciones de recepción y problematizamos el sentido de “texto” y “escritura” en el pensamiento derridiano. Como mostramos, estas nociones no se vinculan con ninguna “hiperbolización” del lenguaje, sino más bien su ruina.

Summary During the nineteenth century French chemistry was marked by an outstanding number of Alsation chemists whose scientific contributions cannot be ignored. Especially following the Franco-Prussian War, their regional origin was given a particular importance as a means of affirming their singularity on the French scientific scene. However, some questions may be raised: can we distinguish the Alsatians from other French chemists before 1870? Were they a homogeneous group sharing a common origin? The aim of this article therefore, is, to (...) show that by their theoretical options within chemistry, their personal and professional relationships, as well as by their participation in various common initiatives, they organized themselves both formally and informally within the Parisian scientific community. Amongst these forms of organization the research school of Charles Adolphe Wurtz (1817?84) emerges as the nucleus of what we may envisage as a network of Alsatian chemists working in Paris, in the second half of the nineteenth century. (shrink)

The journal ESPACIO of the Development Research Center (CINDES), in Quito Ecuador, has been kind to offer us the publication of a series of un-edited interviews made with outstanding researchers in social sciences, politics and philosophy, related to the historic present of Latin American soci..

Questo articolo analizza la relazione tra la politica della memoria, le misure di austerità, le implicazioni del neoliberismo e l'importanza dell'agency collettiva in Brasile. Lo studio analizza come l'attuazione delle misure di austerità tra il 2016 e il 2022 abbia influito sulla spesa governativa per le iniziative legate alla memoria della dittatura nel Paese. La riduzione dei finanziamenti dovuta a misure come l'emendamento “Expanding Cap” ha danneggiato diversi progetti in corso. L'articolo discute l'impatto più ampio del neoliberismo sulla memoria attraverso (...) la prospettiva che il ragionamento neoliberale potrebbe essere apatico nei confronti della memoria collettiva, ma, così facendo, potrebbe diventare un incubatore di pratiche autoritarie. Pertanto, l'agenzia collettiva e un ruolo più ampio della società civile sono pietre miliari nella trasmissione delle memorie collettive di un passato violento. (shrink)